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In the STEP UP trial, the higher semaglutide dose led to an average weight loss of 18.7% in participants without type 2 diabetes, compared to 16% for those treated with the standard dose and four percent with placebo

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Mar 2 2018;34(2)doi:10.1515/hmbci-2017-0067 Facchinetti F, Orru B, Grandi G, Unfer V