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To rule out inferiority, the FDA required CVOTs to show an upper boundary risk ratio of 1.3 (post approval), utilizing a two-sided 95% confidence interval (CI), for major adverse cardiovascular events (MACE) [55]
Their effects on weight loss may be due to other mechanisms and methods of administration
Commercial applications like Relispray (a turmeric-based spray bandage) leverage curcumins wound-healing properties (Lagoa et al., 2025)
As supplied for research it is for in-vitro laboratory use only and is not an approved drug, supplement, or medical product
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