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Folate is critical in the metabolism of nucleic acid precursors and several amino acids, as well as in methylation reactions
Once used for liver and neurological conditions, it's now being misused by unregulated beauty clinics
Iacobellis et al
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The omega-3 fatty acids docosahexaenoic acid and eicosapentaenoic acid serve a role in reducing the resistance of tumor cells to bortezomib by activating the serine synthesis pathway, mitochondrial folate cycle, methionine cycle-associated GSH synthesis and ChaC1-mediated GSH degradation in tumor cells, ultimately promoting GSH degradation (138)
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