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Verdict: Direct comparison difficult due to different trial designs, but retatrutide's advantage appears substantial even accounting for flexible vs fixed dosing
Zhang L
& Ellegaard, J
Tirzepatide's GI side effects (nausea, diarrhea, vomiting, constipation) are similar in type but some analyses suggest modestly higher rates than semaglutide, particularly at the highest doses
The recommended fridge duration for semaglutide varies depending on the specific product and manufacturer
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