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The rapidly acting antidepressant ketamine and the mGlu2/3 receptor antagonist LY341495 rapidly engage dopaminergic mood circuits
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Marys Hospital, The Catholic University of Korea) to evaluate the safety, tolerability, and pharmacokinetics of subcutaneous PG-102 in healthy individuals with overweight (body mass index 2530 kg/m), with exploratory pharmacodynamic and biomarker assessments
Consistently, genetically predicted acetyl-carnitine was also related to higher risk of CAD (OR 1.06, 95% CI 1.01 to 1.10) and heart failure (OR 1.07, 95% CI 1.01 to 1.14) (Additional file 2: Fig