The study examined genetic variants in the GLP1R gene across diverse populations, including 408,774 white British individuals, 50,314 white Europeans, 7,667 South Asians, 10,437 individuals of multiple ancestries, and 7,641 African-Caribbeans
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14,15 Another meta-analysis of 93 clinical trials showed that GLP-1 RAs increased the risk of early-stage DR compared with placebo, with this effect being driven by albiglutide in particular
When switching from semaglutide to tirzepatide, it is important to consult with a medical provider for a gradual transition
The simulated population consisted of adults with obesity or overweight, defined as a body mass index (BMI) of 30 kg/m or27 kg/m with at least one obesity-related complication