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The same results were obtained in a cross-sectional study in Najaf city, which also found that among 1153 patients with COVID-19, two-thirds of them were males

MDM2 mediates the ubiquitin-dependent degradation of SPY1, resulting in a downregulation of SPY1 expression, which in turn upregulates the expression of ALOX15 and growth differentiation factor 15 (GDF15), while decreasing the levels of GCH1, GPX4, and GSH

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