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Supplementary information Supplementary Tables 15 (download XLSX Supplementary Table 1 Baseline demographics and clinical characteristics of the patients in the SELECT trial
Cost Optimization Some users report stretching medication supply through microdosing: Extended pen life: Using lower total weekly doses during maintenance Shared supply: Some households with multiple users (controversial) Insurance gap coverage: Stretching doses during authorization delays Warning: Cost-motivated dose reduction may compromise efficacy
Slight differences in meal composition, hydration, injection timing, and injection-site reactions can change whether symptoms resolve or linger
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These medications are relatively expensive and patients may need to use them continuously to maintain weight loss
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