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Search strategy and study selection We conducted a comprehensive search through PubMed, Scopus, and Web of Science databases to identify pertinent studies from their inception until March 2024
The 1:1 ratio matters because both receptors have strong genetic validation for obesity
Cell Metab (2006) 4:391406
However, emerging human data have not shown an increased risk of major birth defects when GLP-1s were used during early pregnancy
The body naturally produces GLP-1 in the intestines in response to food intake, and this plays a key role in regulating appetite and blood glucose levels and improving satiety (the feeling of fullness after eating)
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