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Its primary roles include stimulating insulin secretion, inhibiting glucagon release, and promoting satiety

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If they persist beyond a full titration cycle, your clinician can adjust your plan sometimes by extending the time at a given dose before moving up

doi: 10.3389/fphys.2025.1683271 Received 10 August 2025 Revised 16 October 2025 Accepted 17 October 2025 Published 28 November 2025 Volume 16 - 2025 Edited by Xuchang Zhou, The First Affiliated Hospital of Xiamen University, China Reviewed by Qutaiba Qasim, University of Basrah, Iraq Rehab Abohashem, National Research Centre, Egypt Updates Copyright 2025 Samir, Hassan, Elmowafy, Ebrahim, Albadawi, Albadrani, Owaydhah and Elhadidy

M., Cobley, J