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Cancer 106 (1), 189198
The risk of hypoglycemia with tirzepatide remains low, consistent with other GLP-1 receptor agonists, particularly in the absence of concomitant Insulin or sulfonylureas (Frias et al
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A likely explanation is that the BAs bound to a sequestrant into the intestinal lumen can't be absorbed and hence travel more distally in the GI tract where the complexes are still capable to activate the TGR5 expressing colonic L-cells
Simply propping up extra pillows does not work because it creates a bend at the waist that actually increases abdominal pressure
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