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The high proline content (4 of 15 residues, including a triple Pro-Pro-Pro stretch at positions 3 to 5) gives BPC-157 unusually good resistance to gastric and intestinal proteases, which is why some published animal work uses oral administration
Most products suggest twice-daily application for optimal results
Conclusion MOTS-C is a scientifically interesting mitochondrial-derived peptide with proposed roles in metabolic signaling, cellular stress adaptation, glucose regulation, exercise responses, and muscle homeostasis
A., Vargas, S., Francis, W
Even though participants returned the empty containers and self- reported their compliance to be 100%, it is possible that the information provided to study personnel was not accurate and reflective of the actual supplement compliance
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