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Song Y et al
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Additionally, L-OOH is oxidized by Fe 2+ to generate tremendously reactive lipid alkoxyl radicals (LO), which destroy PUFAs through a chain reaction, leading to membrane injury and cell death ( 2+ in the unstable iron pool, preventing the formation of hydroxyl radicals from its reaction with H 2 O 2 (Philpott and Ryu, 2014)
Chem Res Toxicol 6:511518 Pitt JJ, Hauser S (1998) Transient 5-oxoprolinuria and high anion gap metabolic acidosis: clinical and biochemical findings in eleven subjects
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