Recently, the interaction between forkhead box O4 (FOXO4) and p53 has received considerable attention as a target for senescent cells
JHU083 also inhibits the expression of indoleamine 2,3-dioxygenase (IDO) in tumor cells, leading to decreased kynurenine levels and delayed tumor growth and metastasis by enhancing antitumor immune response (Oh et al., 2020)
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