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Higher levels of pro-inflammatory cytokines and glial cell markers were observed, and stool samples had higher concentrations of inflammatory mediators such as TNF-, IL-1, IL-6, and IFN- in PD patients colon biopsy tissues, which indicate gastrointestinal inflammation (84) (Figure 2)
doi: 10.3389/fgene.2020.630186 Received 16 November 2020 Accepted 21 December 2020 Published 21 January 2021 Volume 11 - 2020 Edited by Ilia Stambler, Independent Researcher, Tel Aviv, Israel Reviewed by Idan Shalev, Pennsylvania State University (PSU), United States
As research advances, integrating genetic, molecular, and clinical insights will be critical to developing effective therapies that not only alleviate symptoms, but also modify the course of the disease and improve the lives of patients and their families
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