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Excessive accumulation of intraperitoneal iron can lead to the overproduction of ROS and the enhanced activation of nuclear factor-kappaB (NF-B)
J., Imbens, G
Because rapamycin, which extends mouse lifespan 31 , can reverse age-related diastolic dysfunction and restore a more youthful metabolome in the aged myocardium 32 , we next evaluated metabolomic changes in Young, Old Con, and Old mAb female-treated hearts
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