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The SELECT trial is the only large-scale cardiovascular outcomes trial completed for either drug in an obesity population
In the UK, these medications are available by prescription only for individuals with a BMI of 30 or above (or 27 or above with weight-related health conditions)
Standard GLP-1/GIP agonists activate both the cAMP (G-protein) and beta-arrestin signaling pathways
Regular check-ins with your healthcare provider are also key
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