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Semaglutide is used to treat Type 2 diabetes mellitus as monotherapy (if metformin inappropriate), or in combination with other antidiabetic drugs (including insulin) if existing treatment fails to achieve adequate glycaemic control
Limitations of the E3 ligase repertoire and heterogeneity in tissue expression Current PROTAC development strategies are constrained by the limited E3 ligase repertoire, with most TPD studies relying on a small number of members such as CRBN and VHL
What to track monthly Progress photos: Take consistent photos under the same lighting, at the same angle, in the same clothing
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