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273 In addition, in a rat model of inflammatory OA induced by monoiodoacetic acid (MIA), researchers have shown that the activation of GLP-1R triggers the PKA/CREB signaling pathway, leading to a reduction in cartilage inflammation

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The FDA will consider the panels advice, along with the agencys own scientific review and other regulatory factors, before making a final determination

Possible side effects may include mild pain or swelling at the injection site, headache, nausea, or anxiety