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REDEFINE (obesity) and REIMAGINE (T2D) are the main Phase 3 programs, with REDEFINE 1, 2, and 4 already reported
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Contrave is a combination of two existing drugs: naltrexone and bupropion
Mismatches can cause rejections
In rats and mice exposed to semaglutide at clinically relevant doses, researchers observed C-cell adenomas and carcinomas at statistically significant rates compared to control animals
However, it's important to note that many of these studies are observational and do not prove that GLP-1 medications cause the reduced risk
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