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Semaglutide can slow down digestion, which sometimes causes constipation
Moreover, several studies showed no differences in insulin or IR in obese PWS patients and controls [3, 4]
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People taking them often feel full sooner, eat less, and their bodies metabolize food more effectively
The slowing of gastric emptying by GLP-1 is subject to rapid tachyphylaxis following chronic exposure, likely at the level of the vagus nerve
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