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8 For example, in NSCLC, COL11A1 CAFs accumulate at tumor margins, deposit dense ECM components (COL1A1, COL3A1), and physically restrict CD8 T-cell infiltration by interacting with tumor DDR1
Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS, et al
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Patients should seek urgent medical attention if they develop severe, persistent abdominal pain
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