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Patel R, et al
GHK-Cu shifts fibroblast gene expression toward extracellular-matrix synthesis, antioxidant defense, and DNA repair at low-nanomolar concentrations, and supplies copper for lysyl oxidase the enzyme that crosslinks collagen fibers into load-bearing structure [4] [5]
European Journal of Endocrinology lvag123
Therefore, ZEB1 promotes hypermethylation of the ER promoter, leading to estrogen inhibitor resistance in breast cancer [52]
4 June 2015
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