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During mastication they are enzimatically converted into thiocyanates, goitrin metabolites, that cause a competitive inhibition of the sodium/iodide symporter, thus inhibiting the thyroid hormones synthesis and possibly causing hypothyroidism [156]
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DAla2-GIP-GLU-PAL protects against cognitive deficits and pathology in APP/PS1 mice by inhibiting neuroinflammation and upregulating cAMP/PKA/CREB signaling pathways
doi: 10.1016/j.jchemneu.2019.01.006 61 KimYTaralloVKerurNYasumaTGelfandBDBastos-CarvalhoAet al
There is also early evidence and ongoing confirmatory trials that GLP-1 drugs could work in Alzheimers and even addiction
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