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Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors
In the liver, glutathione-S-transferases can attach glutathione to certain compounds, supporting their processing and elimination
In contrast, the beneficial effects of SGLT2 inhibitors on albuminuria and eGFR decline in DKD were demonstrated by EMPA-REG OUTCOME (Wanner et al., 2016), CANagliflozin cardioVascular Assessment Study (CANVAS) (Perkovic et al., 2018), DECLARE-TIMI58 (Mosenzon et al., 2019b), and Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) (Perkovic et al., 2019)
26 Investigators have also combined ALA with glutathione in previous studies
