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In secondo luogo, necessario che il paziente abbia interrotto o regolarizzato il trattamento farmacologico, e che le condizioni metaboliche generali (glicemia, pressione arteriosa, profilo lipidico) siano ben controllate

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GHK-Cu stimulates angiogenesis primarily through upregulation of key growth factors including vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF/FGF-2), with research demonstrating that GHK-Cu at nanomolar concentrations increases VEGF expression in dermal fibroblasts and stimulates human umbilical vein endothelial cell (HUVEC) proliferation through enhanced VEGF and FGF-2 expression

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The immunomodulatory roles of GLP-1RAs, potentially mediated through AMPK pathway activation, may partly explain these distinctions, as this mechanism could influence viral reactivation [17]

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