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Drug reaction One case study found that specific drugs are more likely than others to cause hyperpigmentation
The initial dose is low, and your doctor may adjust it after one week
The mechanisms driving these effects are multifaceted, involving the suppression of neuroinflammation via the TLR4/NF-B pathway and restoration of brain energy metabolism through the activation of the AMPK and SIRT1/GLUT4 signaling cascades (Wang et al., 2023
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10.1042/BCJ20210071 14 FriedrichsenM.BreitschaftA.TadayonS.WizertA.SkovgaardD
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