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In people with reduced ALDH2 levels (and thus more acetaldehyde), alcohol is more likely to induce asthma.[ref] One study explains: Impaired ALDH2 activity leads to high peak levels of acetaldehyde and to histamine release. Studies show that inhaling acetaldehyde induces histamine-mediated airway constriction, such as is seen in asthma.[ref] Hangovers and histamine A recent animal study sheds light on the age-old question of what causes hangover symptoms
Studies suggest this rebalancing occurs through effects on thymic peptide signaling and restoration of neuroendocrine-immune system communication that deteriorates with aging
In the oral mucosa, melanocytes are observed in a ratio of about 1 melanocyte to 10 basal cells
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LA deficiency leads to an impaired more permeable skin barrier and the topical application of LA-rich sunflower oil can fix this issue rapidly (while oleic-rich olive oil did not have the same barrier repairing effect)
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