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Est contraindicada en pacientes con antecedentes de carcinoma medular de tiroides o sndrome MEN2

In fact, there was a trend toward a lower risk, although this did not reach statistical significance

Intense interest in the TKTL1 gene, and its encoded protein, was stimulated because it was shown that the level of TKTL1 expression correlated with poor patient outcomes and metastasis in many solid tumors