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10.1016/j.jhep.2013.01.038 5

Oral activity of the growth hormone releasing peptide His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 in rats, dogs and monkeys

Or to frame it differently, researchers using oral acetate BPC-157 may have been receiving only a fraction of the intended dose, which could explain the inconsistent results that some users reported with oral BPC-157 protocols

This leads us to our next critical topic

While a few smaller peptides or those with special modifications might have slightly better oral bioavailability, injectable administration remains the gold standard for most peptide research to ensure efficacy.