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In vitro studies, HepG2 cells treated with palmitic acid (PA) were found that dulaglutide significantly reduced liver lipid accumulation and gene expression related to lipid drop-binding proteins, de novo adipogenesis and TG synthesis
PubMed Enebo, L.B., Berthelsen, K.K., Kankam, M., Lund, M.T., Rubino, D., Satylganova, A., Lau, D.C.W., & le Roux, C.W
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Clinical studies have shown that patients using semaglutide experience average reductions in LDL cholesterol and triglycerides, partly due to weight loss itself and partly due to direct metabolic effects of GLP-1 signaling
Presented for research literature review only Kavadias D et al
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