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In general, patients with moderate or severe acne tend to have overactive sebaceous glands that produce too much oil, which clogs pores, trapping bacteria in the pore, which then festers, creating painful blemishes

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An estimated 6785% of women with the condition have serum 25(OH)D below 20 ng/mL, so the odds your own level is low are high and low levels correlate with menstrual irregularity, hyperandrogenism, and insulin resistance