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If the GSH:GSSG ratio had been recognized as a clinical biomarker when Mills discovered glutathione peroxidase in 1957, standard blood panels might have included redox status alongside glucose and cholesterol

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[6] Specifically, in this study conducted by Patrick Jacobs and colleagues, 24 healthy, exercise trained men consumed either 4.5 grams of GPLC or a placebo on two different days separated by one week (double blind, cross-over study design)

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