For patients with diabetes, preserving muscle is especially important because skeletal muscle plays a key role in glucose disposal and insulin sensitivity
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Key trends include increased demand for pharmacological weight management, heightened adoption of GLP-1 therapies beyond diabetes, and improved patient adherence to long-term treatments
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TRIUMPH-4 (28.7% weight loss, knee OA population, December 2025), TRIUMPH-1 (28.3%, general obesity, May 2026), TRANSCEND-T2D-1 (-2.0% HbA1c, 16.8% weight loss, June 2026), TRIUMPH-2 (20.8% weight loss, obesity + diabetes, July 23, 2026), and TRIUMPH-3 (22.6% weight loss, obesity + cardiovascular disease, July 23, 2026) have all reported positive results