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Key Takeaway: Coldness on Mounjaro is rarely due to a single cause

GLP-1 analogues delay gastric emptying ( When initiating GLP-1based therapy, clinicians should adhere to the principle of do no harm , particularly during the early phases of treatment when gastrointestinal adverse effects are most likely to emerge ( Potentially the easiest way to prevent nausea and vomiting is by starting at a low dose ( In most cases of Grade 1 or 2 nausea, maintaining the current dose for one to two additional dosing intervals is sufficient to allow symptom resolution

Dose Range: 212 mg weekly with gradual 4-week titration steps [3] [4]

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PubChem Compound Summary for CID 56841945