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however, several hypotheses informed largely by evidence from related GLP-1 receptor agonist classes have been proposed: Weight loss-mediated reduction in vascular resistance , as excess adiposity is a well-established driver of hypertension
E., Smith, A
The medication is approved for adults with type 2 diabetes when blood sugar control is not sufficient with diet and exercise alone
Known gastroparesis or severe functional dyspepsia History of pancreatitis (particularly unexplained) Active gallbladder disease or prior complications Severe IBS-C unresponsive to standard measures Significant reflux worsened by delayed emptying Planned procedures under sedation/general anesthesia (coordinate care) These arent automatic nos, but they do call for individualized riskbenefit discussions
A clinic should only source from the first group
