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Krug et al., 2019)
For weight management, only semaglutide (Wegovy) and liraglutide (Saxenda) are licensed, with specific eligibility criteria outlined in NICE guidance
The Evolution Beyond Single-Agent Semaglutide Following semaglutide's success, researchers developed dual-pathway medications like tirzepatide that activate both GLP-1 and GIP receptors simultaneously
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These medications mimic a naturally occurring hormone, glucagon-like peptide-1 (GLP-1), which helps regulate appetite, slow digestion, and increase feelings of fullness
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