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Participants with prior GLP-1RA prescriptions had average AUDIT-C scores approximately 8% lower than those in the future-prescription group, although the difference was not statistically significant

Rybelsus is not used for treating type 1 diabetes

It is the first approved medication for long-term weight management in adults with obesity or overweight

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Binding triggers Gs-coupled adenylyl cyclase activation, raising intracellular cAMP and downstream protein kinase A (PKA) signalling in each target tissue