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Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging
Escudier S, Pereira-Leahy JM, Goodacre AM, Drach JW, Cork MA, Trujillo MJ, Weier HU, Keating MJ, Andreeff M
Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR mutant lung cancer
Some practitioners advocate weight-based dosing (e.g., 2.5-5 g/kg daily), while others use fixed doses (250-500 g daily) regardless of body size
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