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When coated with chitosan and decorated with folic acid, gold nanoparticles combine the metal core's optical properties and high surface area with the polysaccharide's pH-responsive drug release and membrane-interactive characteristics [131]
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Combined with gut-healing protocols , this approach addresses histamine intolerance from both the production and clearance sides
No controlled trial has established either combination
its a well-documented risk with synthetic peptides that has ended pharmaceutical development programs
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