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People are most at risk if they eat very little food while drinking too much plain water, or if they become very dehydrated

Because of the slowed gastric emptying, many patients have gastrointestinal side effects that can often limit a patients ability to take these drugsespecially at the high doses recommended for weight loss

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Official product information European Medicines Agency

2.2.3 Comparator(s)/control Other glucose-lowering drugs used to treat type 2 diabetes, such as insulin, sulfonylureas, DPP-4 inhibitors, SGLT2 inhibitors, metformin, and thiazolidinediones, will serve as comparators