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The functions of the BBB and BCB include: protection of the brain from pathogens and toxic metabolites, the separation of the brain and periphery neurotransmitter pools, intake of essential nutrients and discharge of metabolites, and maintaining the immune privilege of the brain, where the immune activity is mainly accomplished by internal microglia rather than, e.g., bone marrow or thymus-derived immune cells (Galea et al., 2007
56, e01329-17
Drug Interactions : Glutathione may interact with certain medications, particularly those that affect liver metabolism
Gclc and Nrf2 mRNA levels were decreased in L-DKO mice three weeks following injection of the AAV-TBG-Cre virus (Fig
