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NIDDK also notes that overweight and obesity can increase the risk of many health problems

When people lose weight quickly with GLP-1 medications like semaglutide, their bodies break down both fat and muscle tissuea process called lean mass loss

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During treatment with Wegovy , patients should contact their healthcare provider if they experience: Severe or persistent nausea, vomiting, or diarrhoea that affects daily functioning or causes dehydration Severe abdominal pain, particularly if accompanied by nausea and vomiting (potential pancreatitis) Symptoms of gallbladder disease (pain in right upper abdomen, fever, jaundice) Signs of allergic reaction including rash, itching, or difficulty breathing Mood changes or depression (report but note no established causal link) Symptoms of hypoglycaemia if taking diabetes medications concurrently Unexplained lumps or swelling in the neck For patients with diabetes: changes in vision that could indicate diabetic retinopathy If considering changes to weight loss treatment , including questions about combining medications or switching therapies, patients must discuss this with their prescribing physician