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Exocrine pancreatic insufficiency: The pancreas produces enzymes that are essential for digesting food and preparing nutrients for absorption
Among the 25 studies included in the qualitative synthesis (16 in the meta-analysis), 15 focused specifically on serum cobalamin changes (reported by baseline and post-treatment means and standard deviations in pg/mL) and 10 reported homocysteine outcomes (means and standard deviations in mmol/L)
higher doses may be used in some circumstances in line with BSH guidance, as passive absorption can partially compensate for absent intrinsic factor at high doses
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