For a patient with Type 2 diabetes and established heart disease, choosing a GLP-1 agonist over insulin could provide meaningful protection against future cardiovascular events, above and beyond blood sugar control
It will be interesting to see whether the new and effective therapeutic alternatives under development for obesity enable a more effective decrease in body weight, which, in turn, could be beneficial for the outcome of immune-mediated dermatoses
But the brain proved too noisy
The ketogenic diet has also emerged as a powerful alternative that helps patients achieve substantial weight reduction through a high-fat, low-carbohydrate approach
In this context, disruption of temporal coordination, rather than hormone abundance alone, may limit effective engagement of melatonin-dependent immunoregulatory pathways