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Accordingly, we encourage the adoption of GLP-1RA plus SGLT2i combination therapy in patients with T2DM and established atherosclerotic cardiovascular disease (ASCVD) or multiple risk factors for ASCVD (i.e., age 55 years, overweight/obesity, dyslipidemia, hypertension, current tobacco use, left ventricular hypertrophy, and/or proteinuria)
By the time a patient qualifies for semaglutide, chronic disease changes have been developing for many years
Once they incorporate those changes, they do lose weight at a quicker clip. Dr
Neurotherapeutics 18 , 962978 (2021)
Food and Drug Administration (FDA) first approved Topamax for the treatment of seizures in 1996
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