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This situation feels different from other drug classes because it is: diabetes and obesity are massive markets, and beyond the FDA approved indicated populations, theres a swath of people interested in getting their hands on GLP-1 agonists off-label to help them lose a few extra pounds
Key Points A small percentage of patients experience fatigue on semaglutide, often moreso with higher doses Those who do experience fatigue find it improves as their body adjusts to the medication Staying hydrated, maintaining balanced nutrition, and gradually increasing your dose can help reduce fatigue Long-term studies show that after initial side effects subside, most people actually report better energy levels as they lose weight Feeling tired while taking semaglutide (Ozempic or Wegovy)
10.1038/ajh.2009.244 9 Asirvatham-JeyarajN.FiegeJ
Age affects skin's ability to recover
However, responses vary, and semaglutide should not be used as a primary treatment for blood pressure without guidance from a healthcare professional.
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