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The dose titration starts at 0.25mg and increases every four weeks through 0.5mg, 1mg, 1.7mg, and 2.4mg, then continues up to 3.6mg and the maintenance dose of 7.2mg at around week 32
A comparison of efficacy and safety of vildagliptin and gliclazide in combination with metformin in patients with Type 2 diabetes inadequately controlled with metformin alone: a 52-week, randomized study
Is NAD+ Therapy safe
In vivo data were analyzed with one-way analysis of variance (ANOVA) followed by Tukey post hoc analysis (acute food intake, db / db HbA 1C data)
Trial STEP TEENS (Weghuber et al., NEJM 2022) Design Phase 3 / 68 weeks Population 201 adolescents (12-17) with obesity Key result -16.1% BMI reduction vs +0.6% placebo
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