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32, 33 Numerous stimulants activate PSCs, including activation of some G-protein-coupled receptors (PGE2, angiotensin, CCK-A, CCK-B)
However, this same action can lead to gastrointestinal side effects, with abdominal distension (bloating) being a commonly reported complaint
Anticancer Res 39:66536660
They work by enhancing insulin secretion in a glucose-dependent manner, meaning they help your body produce more insulin when blood sugar is high and back off when blood sugar is normal
adults are obese and an additional 30% are considered overweight
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