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By week 12, clinical trial participants lost an average of 8.7% of their body weight across all doses, with the 12mg group reaching close to 10%

Since then, it has become an immensely popular and useful molecule, both as a supplement and a medication, and is the 104th most prescribed medication in the United States as of 2023

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Researchers now believe GLP-1 meds may work by changing how the brains reward system responds, basically making addictive behaviors feel less exciting

However, human clinical trials have not documented MTC cases directly attributable to GLP-1 therapy, despite millions of doses administered globally